Our Services

Curated study outlines that are unique to each client.

Safety Testing

Multiple pathways for testing Skin Biocompatibility, Sensitization & Irritation. Safety-In-Use studies with specialty physician investigators and targeted subject populations.

Clinical Safety Testing consists of:

Patch Testing -Standard and Specialized

HRIPT: all variations run
Cumulative Irritation
Primary Irritation
Repat Open Application Tests
Chamber Scarifications
Product Breakdown Testing
Photoallergy / Phototoxicity
Comedogenicity Assay

Facial Sting Assay

Ambient and stressed conditions

Modified Usage Tests

Safety-In-Use – standard and specialized for unique product types

All ages from pediatric to geriatric, targeted area to full body treatment
Designed to look for tolerance and acceptability with real-life usage
Can add skin wellness endpoints with instrumentation
Standard routine studies include dermal safety in use with and without an ophthalmologist, pediatric safety in use, ophthalmologist safety in use, acnegencity/ non-comedogencity
Standard-specific recruitment types:
- Acne, Acne-prone
- Sensitive skin, sensitive eyes, sensitive lips
- Contact lens wearers
- Capability for specific or all skin types (oily, dry, combination, normal)
- Capability for specific or all skin tones (full Fitzpatrick representation)

Research: Methodology and Innovation

Idea lab and research wing dedicated to novel methodology development, irritation & inflammation assays, and skin research. From proof-of-concept exploration to custom protocols.

Environmentally Controlled Lab Tests:

Environmental Cycling
- Unique environmentally controlled clinical lab space to simulate various standard and extreme dry, hot, or cold conditions (cold winter, hot summer, travel airplane, etc.)
Sensitive Skin Research
Wound Healing Models
Specialized support for probes for skin biomarkers, proteins, collagen, peptides, etc.

Efficacy Evaluations & Claim Support

Specialty imaging. Advanced Bio-instrumentation. Expertly trained & validated visual graders for various visual and tactile assessments of the skin. Specialty environmental protection /travel claims. Skin sampling (non-invasive to biopsy.)

Efficacy Testing:

Large sample size
Validated expert grader for skin attributes
On Site Hair Salon
Make-up Efficacy Tests
Skin sampling pre and post treatment
Aesthetic treatment room for facial treatments
- Procedures including acid peels, fillers, IPL, lasers, and more.
Specialty Imaging and Advanced Bioinstrumentation

Consumer Research

Targeted questionnaires with statistical analysis.

Types of Researches:

In-home/on-site usage tests with targeted consumer questionnaires and statistical analysis
Audio and Video testimonials
Focus Groups

Aesthetics

Aesthetic treatments are either done at our facility or at our partnering Aesthetic Facility:

Chemical Peels (Glycolic, TCA, etc)
Injectables
Microneedling
Laser Treatments
- CO2 Laser Resurfacing
- IPL

Biospecimen Collection

Custom Bio Specimen Collection:
- Saliva
- Blood Serum
- Tape-Stripping / Skin layers by Skin Squame
- Adhesive Disc
- Full Thickness Skin Biopsy
  - Isolated frozen/banked or fresh/viable (fresh/ viable samples available depending on customer proximity to the collection site)
- Dermal Interstitial Fluid (dISF)
- Blister Formation and Fluid Extraction
- Vaginal Fluid Sampling
- Skin and Vaginal Flora Sampling for Microbiome Analysis
Healthy and Disease cohorts (Atopic Dermatitis, Rosacea, Diabetes, Psoriasis, HS, etc.)
On-site Cryostorage and global shipping via courier service
Histology capabilities include sectioning, slides, blocks, staining, and photography

Skin Sampling

Types of Sampling:

Tissue by full-thickness biopsy
Skin layers by Skin Squame Adhesive Disc
Skin Flora by swabbing for the Microbiome
On-site Cryostorage and global shipping via courier service
Histology includes sectioning, slides, blocks, staining, and photography

Instrumentation

Types of Instrumentation:

Imaging
- Canfield Visia – CR
- Canfield Visia – CR Gen 5 with Primos 3D
- Vectra M3 3D imaging System
- Antera 3D Camera C2
- Canfield IntelliStudio Gen III
- CK Visioscan
Chronometer, Cutometer, TEWL (RG-1 and GP SKIN), Sebumeter, Skin-pH-Meter
AGE Reader Mu
Multiport Solar Stimulator

Consulting Services

We provide consulting for pre-clinical, clinical research, regulatory, and postmarket product issues. We refer to our experts to help with your needs.